Carlos Andres Gallegos-Riofrio will disusss the Symphony Project, an international, cross-institutional collaboration exploring the relationship between landscape and human health across the rural-urban spectrum in Ecuador's central highlands. Using a transdisciplinary and participatory approach, this pilot study examines the interconnectedness of human and ecosystem health, focusing on cultural, social, and behavioral influences. The project employs a mixed-methods design, integrating environmental, biophysiological, psychometric, and qualitative measures across three residence types: Andean agroecosystems, agro-industrial farms, and urban spaces. Key data include soil health, biodiversity, crop associativity, and microbiome analysis. Biophysiological indicators like gut and nasal microbiomes, pesticide exposure, heart rate variability, physical activity, and inflammation markers are analyzed alongside health and mental health assessments. A multi-component survey examines socioeconomic conditions, agricultural practices, epidemiological profiles, and lifestyle factors. This presentation will present the team and the communities, highlight key lessons and preliminary findings, aiming to unveil insights into holistic and sustainable ecological health in diverse residence conditions, with implications for fostering an Agroecological Transition for Planetary Health.